Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep779 | Reproductive and Developmental Endocrinology | ECE2020

Coagulation abnormalities in patients with klinefelter syndrome compared to age-matched healthy controls: Cross-sectional assessment by thrombin generation test

Indirli Rita , Profka Eriselda , Vena Walter , Cangiano Biagio , Pizzocaro Alessandro , Bonomi Marco , Clerici Marigrazia , Scalambrino Erica , Mazziotti Gherardo , Lania Andrea , Arosio Maura , Mantovani Giovanna , Tripodi Armando , Ferrante Emanuele

Introduction: Klinefelter syndrome (KS) is known to be associated with an increased risk of venous thromboembolism and arterial thrombosis, but the aetiology behind this prothrombotic status has not been fully elucidated. The aim of this study was to cross-sectionally investigate the coagulative state in subjects with KS compared to age-matched healthy males.Methods: Coagulation factors assessment, clinical characteristics collection and thrombin generat...